If you’re using CBD for another purpose, such as for anxiety relief or as a means of establishing proper overall health and wellness, the following information will be equally as important for you to absorb. Most are https://ecosoberhouse.com/ familiar with THC, the cannabinoid responsible for the intoxicating and euphoric effects of marijuana that causes “impairment.” THC’s molecular form is very similar to our bodies’ naturally occurring endogenous neurotransmitters. The purpose of the endocannabinoid system is to regulate a variety of bodily functions such as mood, memory, fertility, appetite, hormones, and responses to pain or stress.

What is CBD?

cannabidiol

Cannabis may or may not be legal for medical or recreational use depending on the laws in your state. The effects of cannabis vary from person to person and depend on many variables, including type, dosage, frequency of use, and interactions with current medications. If you are interested in using cannabis in any form, discuss it with your healthcare provider or pharmacist. Unlike prescription medications, cannabis purchased from dispensaries and recreationally is not regulated by the FDA. Unlike THC, CBD won’t get you high, but it shows promise as a treatment for epilepsy, anxiety, depression, pain, inflammation, cancer, and more. You’ve probably heard a lot about marijuana as more and more states legalize it.

Medications changed by the liver (Cytochrome P450 1A2 (CYP1A substrates) interacts with CANNABIDIOL (CBD)

  • Some studies suggest it might help with gut issues like irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD), but results have been mixed—likely due to differences in dose, delivery method, and individual health.
  • In case of Alzheimer’s disease (AD), studies in mice and rats showed reduced amyloid beta neuroinflammation (linked to reduced interleukin IL-6 and microglial activation) after CBD treatment.
  • For example, high doses of CBD (upward of 600mg daily) seem to be more effective for conditions like epilepsy, whereas low doses are potentially effective for anxiety.
  • As one study put it, people should be skeptical of sleep-related claims made by CBD product manufacturers.
  • Yet, RWE on CBD-rich products is scarce (Goodman et al. 2020; Shannon et al. 2019).

Eligible articles included cell culture, animal model, biochemical, and clinical studies. Findings were thematically synthesized by body system, emphasizing mechanisms and implications for health and disease. CBD oils are not regulated in the same way as prescription drugs, so ingredients may not match the label. In one study, 21% of CBD products sold online contained THC—the psychoactive compound is cbd addictive in cannabis.

cannabidiol

Side Effects

As of April 2023, 38 states, three U.S. territories, and the District of Columbia have legalized medical marijuana. The FDA has issued several warnings to companies that market these products and says you should beware before you use them. CBD can even be applied topically to affected muscles or areas of skin for localized relief in the form of topicals and lotions. Unlike most pain medications that are often prescribed by doctors, such as Hydrocodone (prescribed 127,859,000 times in 2017), Oxycodone/OxyContin (16,440,000), and Morphine sulfate (9,658,000), CBD consumption is by no means limited to consuming a capsule.

This review could substantiate and expand the findings of Bergamaschi et al. about CBD favorable safety profile.1 Nonetheless, various areas of CBD research should be extended. alcoholism First, more studies researching CBD side effects after real chronic administration need to be conducted. Many so-called chronic administration studies, cited here were only a couple of weeks long. Second, many trials were conducted with a small number of individuals only. To perform a throrough general safety evaluation, more individuals have to be recruited into future clinical trials.